Product Code Database
Bernard Peyrilhe (1735–1804) was a French people surgeon, known as one of the founders of experimental cancer research. (2025). 9781118022870, Wiley-Blackwell. ISBN 9781118022870 Peyrilhe was born in Pompignan, and became a lecturer at the Paris School of Surgery ( nocat=true).
In 1773, Peyrilhe was studying for a PhD, (1994). 9780888821652, Hounslow. ISBN 9780888821652 when he wrote the first systematic review of cancer in a prize-winning essay which he submitted to the Academy of Letters and Fine Arts in Lyon in response to an essay competition entitled What is Cancer?. His essay covered the nature of the disease, its growth, treatment, and how a "virus" produced by the tumor caused wasting (cachexia). At the time, the term "virus" meant any substance which came from an animal's body and which could transmit a disease. (1975). 9781468427332, Springer US. ISBN 9781468427332 Peyrilhe attempted to demonstrate this virus, by injecting an emulsion of fluid from a human breast cancer into a wound he had created on the back of a dog. (1983). 9789401706018, Springer Netherlands. ISBN 9789401706018 He kept the dog at his home to observe it, but the dog developed an abscess at the injection site and howled so much that Peyrilhe's servants drowned it. (2025). 9789401791656 ISBN 9789401791656 As is now understood, the transfer of cancerous tissue between species is generally unsuccessful, as the recipient's immune system recognizes cells from a different species as foreign, and destroys them (a graft-versus-host interaction). (1986). 9781468480917, Croom Helm. ISBN 9781468480917
Also in 1773, Peyrihle was the first surgeon to treat breast cancer by radical mastectomy which included both the Pectoralis major and axillary lymph nodes. (2025). 9781444309256, John Wiley & Sons. ISBN 9781444309256 He considered that the risks of amputating the pectoral muscle were outweighed by the otherwise certain outcome of death. (2025). 9781848933644, Pickering & Chatto. ISBN 9781848933644
Peyrilhe also successfully treated ulceration with Phenol, which was, at the time, a recently discovered acid.
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